Prof. Zhu is a distinguished Professor of Shenzhen University, and Dean of the School of Medicine, Shenzhen University, Ph.D Supervisor. He is the head of a number of "973" and "863" programs of the Ministry of Science and Technology of China, head of the National Funding Commission’s innovation team of NSFC, head of the National Funding Commission’s key R&D program, Recipient of the National Outstanding Distinguished Youth Scientist，as well as the head of major and key projects of the National Foundation Commission of China.
Prof. Zhu focuses on the function of the histone modification enzymes and histone modification in the DNA damage response, autophagy and gene regulation, and its role in cancer development. He found a series of important new targets and methods for cancer treatment, which provides an important theoretical basis and experimental support for the accuracy of tumor therapy. He has published more than 160 research papers in leading international journals including Nature, Nature Cell Biology, Molecular Cell, and PNAS which earned more than 15,000 citations. His academic research mainly includes the following three aspects:
1. Identifying a series of histone modifications sites / histone modifying enzymes that participate in the DNA damage response of tumor cells, providing a theoretical basis for tumor radiotherapy and chemotherapy.
2. Revealing the biological functions of histone-modifying enzymes in the multi-level regulation of autophagy.
Consolidating the theoretical basis for the involvement of protein acetylation modification in tumor epigenetic therapy.